Herbal medicinal prescriptions have been helping people without being systematically tested by modern scientific methods. Humans have invented many benefits from natural plants. Medicinal plant extracts are now generally considered as effective therapeutic medicines and they play a vital role in pharmacy. As solanum nigrum, containing various phytoconstituents, are to be useful therapeutically like in treatment of various disease Chronic hepatitis, Infective hepatitis, fever, juice, ointment used for skin problems, as cosmetics. The methanolic extract of the solanum nigrum was prepared by the percolation method and then different concentration of which was tested for its antibacterial and antifungal activity by agar disk diffusion methods. By determining the the zone of inhibition as result methanolic extract of the solanum nigrum was giving good significant activity against test microorganisms, so methanolic extract of the solanum nigrum can be rich source of the antibacterial properties.
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